Adaptive reuse has the potential to maximize the residual utility and value of existing assets through green design methods such as selective disassembly planning. Studies in the field of selective disassembly for adaptive reuse of buildings are scarce and there is no evidence of established methodologies and/or analysis for the optimization of the environmental and financial benefits. In this paper we provide a framework for the multi-objective analysis to obtain several effective selective disassembly plans through the combination of different deconstruction methods. The analysis is delineated in terms of the physical, environmental, and economic constraints of the deconstruction methods per building component. Then, a weighted multi-objective optimization analysis is incorporated to generate the set of noninferior solutions that minimizes environmental impacts and building cost. For adaptive reuse of buildings, the methods described in this study can be used to improve the project outcomes according to specific goals and constraints (e.g. environmental, economic, technical).